A key aspect of hair loss with age is the aging of the hair follicle.[43] Ordinarily, hair follicle renewal is maintained by the stem cells associated with each follicle. Aging of the hair follicle appears to be primed by a sustained cellular response to the DNA damage that accumulates in renewing stem cells during aging.[44] This damage response involves the proteolysis of type XVII collagen by neutrophil elastase in response to the DNA damage in the hair follicle stem cells. Proteolysis of collagen leads to elimination of the damaged cells and then to terminal hair follicle miniaturization.

A good daily multivitamin containing zinc, vitamin B, folate, iron, and calcium is a reasonable choice, although there is no good evidence that vitamins have any meaningful benefit in alopecia. Newer studies suggest that vitamin D may be somewhat helpful and worth considering. Specific vitamin and mineral deficiencies like iron or vitamin B12 may be diagnosed by blood tests and treated.

Women lose hair on an inherited (genetic) basis, too, but female pattern hair loss tends to be more diffuse, with less likelihood of the crown and frontal hairline being lost. Although some women may notice hair thinning as early as their 20s, the pace of hair loss tends to be gradual, often taking years to become obvious to others. There seems to be a normal physiologic thinning that comes with age and occurs in many women in their early to mid-30s. More women have underlying causes of hair loss than men. These include treatable conditions like anemia and thyroid disease and polycystic ovary syndrome (PCOS). These conditions are diagnosed by blood tests along with a historical and physical evidence. Although a few studies have suggested that baldness may be inherited through the mother's family genes, these theories require further testing. Current studies are inconclusive. Although not indicated for female pattern balding, spironolactone (Aldactone) has had some success in treating this condition.


Cyclosporine is used to suppress the immune system in psoriasis and other immune-mediated skin conditions. Although cyclosporine helps hair regrowth in alopecia areata, the risks of using it may outweigh the benefits, as oral cyclosporine can suppress the immune system and increase the risk of serious infection. Other common adverse effects are hypertension and renal impairment, but these are usually reversible.


Anagen is the growth phase. This lasts for about 3 - 5 years, where you can observe your hair growing half an inch every month. Full-length hair from this phase is about 18 - 30 inches long. Studies show that this phase may also be affected by other factors. Asian hair, for example, has been found to have a longer anagen phase. Weather is also a factor; hair growth can be faster in summer than in winter.
When men have hereditary hair loss, they often get a receding hairline. Many men see bald patches, especially on the top of the head. Women, on the other hand, tend to keep their hairline. They see noticeably thinning hair. The first sign of hair loss for many women is a widening part. In rare cases, men see noticeably thinning hair. And in rare cases, women can see a receding hairline or bald patches. The reasons for this are unknown.

Hair transplantation is usually carried out under local anaesthetic. A surgeon will move healthy hair from the back and sides of the head to areas of thinning. The procedure can take between four and eight hours, and additional sessions can be carried out to make hair even thicker. Transplanted hair falls out within a few weeks, but regrows permanently within months. Hair transplants, takes tiny plugs of skin, each which contains a few hairs, and implants the plugs into bald sections. The plugs are generally taken from the back or sides of the scalp. Several transplant sessions may be necessary.[33]
Hormonal changes and medical conditions. A variety of conditions can cause permanent or temporary hair loss, including hormonal changes due to pregnancy, childbirth, menopause and thyroid problems. Medical conditions include alopecia areata (al-o-PEE-she-uh ar-e-A-tuh), which causes patchy hair loss, scalp infections such as ringworm and a hair-pulling disorder called trichotillomania (trik-o-til-o-MAY-nee-uh).
The dermatologist also will carefully look at your scalp and hair. During an exam, the dermatologist may pull on your hair. Sometimes a dermatologist needs to pull out a hair to get the necessary evidence. And sometimes a dermatologist needs to look at the hair on the rest of your body to see whether there is too little or too much hair in other areas.
The earlier you begin treating hair loss, the more effective the treatment will be. Androgenetic alopecia is a condition that gradually worsens over time, so the general rule is that the earlier you seek treatment, the better. “If you’re losing your hair and you have genetic hair loss, using medication such as Propecia or minoxidil is most effective when started early,” says Dr. Robert M. Bernstein, Dr. Wolfeld’s colleague at Bernstein Medical – Center for Hair Restoration. Because not everyone loses hair on the same timeline, you can’t rely on statistics to tell you when you should start treatment. Some men start to notice thinning in their early 20s, while others maintain a thick head of hair well into their 50s. If you suspect that you’re starting to lose your hair and want it to stop, act quickly.
Alopecia mucinosa - also known as follicular mucinosis is an autoimmune disorder. It causes inflammation of the hair follicles which can result in scarring or non-scarring hair loss. This condition can affect any part of the body and can affect both children and adults. If treated early, the hair will grow back. If the condition is too severe, the hair will not grow back.
Are you worried about hair loss? If so, you’re not alone. Roughly 9 out of 10 guys admit that male pattern baldness is something that’s a source of stress and anxiety. By virtue of being here, however, you’ve taken more action than a lot of men have regarding hair loss – you’ve started researching ways to prevent, stop, or reverse male pattern baldness.

The Rogaine rep we spoke to explained that the different packaging (and therefore different prices) has to do with the FDA-approval process: “We discovered in clinical trials that the hair loss patterns between men and women are different,” she said by way of explanation. “Men typically have that bald spot on the crown of their head, where women generally have a general thinning throughout, but concentrated more on the top of the head. So for FDA approval, we had to come up with two different, gender-specific products, so the directions were more explanatory.”
“For hair loss, I routinely recommend multiple vitamins, and especially evening primrose oil. If there’s any sex pattern to it — if a woman is losing hair in partly a male pattern – -then, the problem is there is excessive conversion of testosterone to dihydrotestosterone (DHT) at the level of the hair follicle. Evening primrose oil is an inhibitor of that conversion. So almost anybody with hair loss probably will benefit from evening primrose oil.”
How you wear your hair on a daily basis may influence how healthy it is. “Wearing a tight ponytail, braid, or extensions may, over time, put stress on the hair follicle and lead to hair shedding and permanent loss,” says Dr. Zeichner. He recommends wearing looser styles or wearing your hair down as much as possible. Check out these miracle-working hair products every woman needs.
The cause of female-pattern hair loss is unknown, but doctors said there is a strong genetic component. The risk can come from male or female relatives. Though it looks as if the hair is falling out, that's not really what's happening. Cotsarelis said hair follicles are becoming smaller and producing hairs that may be so small that you can't see them.  Women tend to retain more normal, thick hairs than balding men do.
Like a Ferrari production plant where luxury automobiles are painstakingly assembled from carefully crafted parts, hair growth depends on a number of carefully coordinated systems that work together. It’s no secret that supplements can have a positive effect on other parts of your body, such as your immune system and your heart. Can hair growth supplements have a similar effect on hair loss (androgenetic alopecia) to promote healthy hair growth naturally? Absolutely. In order to understand why, first it’s important to know how your hair grows.
The test involves plucking about 50 hairs from the head, typically at the back of the scalp, so your dermatologist can look at them under a microscope and determine how much of the hair is in the resting, growth, and fall-out phases. Next, a vial of blood is sent to a lab to check hormone and nutrient levels ($100 and up, depending on insurance). If low levels of iron, or high levels of male hormones, like androgens, are contributing to your hair loss, for example, both can be treated through oral supplements or medication. 

As they age, men tend to lose the hair on top of their head, which eventually leaves a horseshoe-shaped ring of hair around the sides. This type of hair loss is called male-pattern baldness. It's caused by genes (from both parents -- the idea that men take after their mother's father is a myth) and it's fueled by the male hormone, testosterone. In female-pattern baldness, the hair loss is different -- it thins throughout the top of the scalp, leaving the hair in front intact.

Laser treatments. Low-level laser therapy (LLLT) is used for the prevention and reversal of hair loss. Also known as red light therapy, cold laser, and soft laser, it is a form of light/heat treatment (therefore generally safer) that is used on cases of pattern baldness and alopecia areata. The procedure uses a device that emits light that penetrates into the scalp. The more commonly used lasers are the excimer, helium-neon and fractional erbium-glass. The procedure can increase the blood flow in the scalp to stimulate the follicles that are in resting or dormant phase to go into anagen, and at the same time, prevent the production of DHT, which destroys the hair follicles.


The cause of female-pattern hair loss is unknown, but doctors said there is a strong genetic component. The risk can come from male or female relatives. Though it looks as if the hair is falling out, that's not really what's happening. Cotsarelis said hair follicles are becoming smaller and producing hairs that may be so small that you can't see them.  Women tend to retain more normal, thick hairs than balding men do.
I stumbled upon this recent study with the title Hair Follicle Characteristics As Early Marker of Type 2 Diabetes. Now that’s a warning bell, if I’ve ever heard one, to get focused on lowering daily sugar consumption and eliminating those blood sugar swings. You know those highs you get when you eat high carb, high sugar and then come crashing down? Yes, those.
Cyclosporine is used to suppress the immune system in psoriasis and other immune-mediated skin conditions. Although cyclosporine helps hair regrowth in alopecia areata, the risks of using it may outweigh the benefits, as oral cyclosporine can suppress the immune system and increase the risk of serious infection. Other common adverse effects are hypertension and renal impairment, but these are usually reversible.

Two of the most common LLLT products in the market are the Hairmax Lasercomb and the Capillus 272. The Lasercomb is a hand-held device that is used to comb the hair for 10-15 minutes every treatment, and takes about eight weeks of use in order to see a noticeable improvement in the thickness and quality of the hair. The Capillus is a laser cap that must be worn, and is more convenient because this can be used at home or even out in public (it can be worn underneath a cap or a turban).
These are the best hair supplement pills I've tried (and I've tried a lot). My hair gets greasier faster so I can tell it's helping to nourish and produce healthy oils at the root. I have definitely noticed faster hair growth when I'm using this product vs when I'm not. I actually only do 1 pill per day instead of the 3 (to save money) and it still works well.
Finasteride inhibits an enzyme that converts testosterone to DHT, or dihydrotestosterone, the hormone that causes hair loss in men, and unlike minoxidil, this drug can actually help hair grow back, as well as prevent further loss. All you have to do is take one pill a day, and according to Dr. Evan Rieder, dermatologist in the Ronald O. Perelman Department of Dermatology at NYU Langone Health, two-thirds of men taking this treatment will see improvements in hair density over time.
Male pattern baldness is caused by a very sensitive reaction to DHT (dihydrotestosterone) – a type of testosterone. This reaction causes the hair follicles (hair roots) to shrink and thereby lose the ability to grow new hair. This process also cuts short the lifespan of hair follicles so you lose hair more quickly. The combination of losing hair more quickly and the slow replacement rate results in baldness.
Anagen effluvium - is hair loss due to treatment with chemotherapy medicines. These medicines target rapidly dividing cells, so affects the actively growing hair cells. Hair grows back after the treatment is finished. This type of hair loss also occurs with radiation therapy but it is localized to the area of treatment. so if treatment is in the hip area you will lose hair in that area but not the hair on your head.

The psychology of hair thinning is a complex issue. Hair is considered an essential part of overall identity: especially for women, for whom it often represents femininity and attractiveness. Men typically associate a full head of hair with youth and vigor. Although they may be aware of pattern baldness in their family, many are uncomfortable talking about the issue. Hair thinning is therefore a sensitive issue for both sexes. For sufferers, it can represent a loss of control and feelings of isolation. People experiencing hair thinning often find themselves in a situation where their physical appearance is at odds with their own self-image and commonly worry that they appear older than they are or less attractive to others. Psychological problems due to baldness, if present, are typically most severe at the onset of symptoms.[11]
There’s also a women’s version (Women’s Rogaine Foam) — but a three-month supply costs $22 more online. The only difference between the two products are the instructions; women are instructed to apply once a day instead of twice. If you’re a woman who doesn’t feel like paying extra for marketing, the men’s product will suffice. A cheaper generic version is Kirkland Signature Minoxidil Foam, but with a longer history on the market and more customer testimonials, Rogaine is our first choice.

DR. WRIGHT: If stomach acid is low, protein isn’t efficiently digested – and hair and nails are made up of… protein! If we are deficient in protein, our bodies know that we can live without hair or nail proteins, but we can’t survive without heart muscle proteins or other important body proteins. So if we are short in supply of protein, the hair or nails are the first to go.


Propecia (finasteride) is a 5 alpha-reductase inhibitor. It works by inhibiting the conversion of testosterone into 5 alpha-dihydrotestosterone (DHT), a hormone that plays an important role in hair loss. Propecia is a prescription medicine and is only approved for use in men. There are other 5 alpha-reductase inhibitors on the market but Propecia is the only one approved for androgenetic alopecia.
Finasteride (Propecia) is used in male-pattern hair loss in a pill form, taken 1 milligram per day. It is not indicated for women and is not recommended in pregnant women. Treatment is effective starting within 6 weeks of treatment. Finasteride causes an increase in hair retention, the weight of hair, and some increase in regrowth. Side effects in about 2% of males, include decreased sex drive, erectile dysfunction, and ejaculatory dysfunction. Treatment should be continued as long as positive results occur. Once treatment is stopped, hair loss resumes.[30]
Laser therapy is available in salons and administered by a hair professional who has been trained in the procedure. Treatment is usually two to three times a week. Generally, each session involves a short 8-15 minute exposure of the scalp to the laser device. There is generally no prescribed period of time that the treatment should be administered, although the more frequent and longer the duration, the more effective results have been observed. Noticeable hair growth can be observed after 12 to 26 weeks of treatment. The LLLT is also prescribed as a complementary treatment in post-operative hair surgery.
“There’s people selling pills and creams and lotions and whatever else, and sometimes you can’t even trust what ingredients they have in there,” he warned us when we spoke to him over the phone. Key takeaway: The hair loss industry is crazy dishonest, so we eliminated any treatments (especially homeopathic methods) that aren’t based in concrete, peer-reviewed science.
“While nutritious eating isn’t going to bring your hair back by any means, eating plenty of protein-rich foods and healthy fats can make the hair that you still have look thicker and shinier.” Skimping on the B vitamins in particular can interfere with the formation of hair cells and, therefore, hair growth. The best sources of Bs are protein-packed foods like chicken, fish, eggs, and pork, as well as leafy greens such as spinach. (These foods are also good for melting belly fat, so it’s a win win).
Common types include: male-pattern hair loss, female-pattern hair loss, alopecia areata, and a thinning of hair known as telogen effluvium.[3] The cause of male-pattern hair loss is a combination of genetics and male hormones, the cause of female pattern hair loss is unclear, the cause of alopecia areata is autoimmune, and the cause of telogen effluvium is typically a physically or psychologically stressful event.[3] Telogen effluvium is very common following pregnancy.[3]
While the drug is generally safe for use, some possible side effects are mild irritation of the scalp, dryness and growth of hair on some parts of the body, especially the sides of the face and hands. In some cases, you might observe some increased hair loss around the first few days of use. If the hair fall continues after two weeks upon application of minoxidil, stop the treatment first and see a doctor.
It will be a mistake if lack of volume does not appear on the list of common hair problems. Happening for both men and women, lack of volume can be the factor that destroys one’s hair and affects his or her look. There are plenty of reasons leading to the lack of volume of flat hair, including thyroid problems, hormone-related conditions, low iron levels, and nutrition. It is believed that the wrong shampoo or inappropriate conditioner can make your hair too heavy and result in lack of volume. Sometimes, product build-up can be the hidden causes for most of the common hair problems, including lack of volume.
The other main hair-loss treatment that was recommended by all four dermatologists I interviewed is finasteride, often called by its brand name Propecia. This FDA-approved medication is only available with a prescription, but these days, it’s found as a generic and ordered online after a virtual consultation, through start-ups like Hims, Keeps, and Lemonaid.
“Once that hair has stopped shedding, it does regrow, at a rate of about a centimeter a month,” said Dr. Senna, who suffered from the condition after each of her pregnancies. She shares photos of herself with patients, to show she can sympathize. In one, her entire frontal hairline clearly is growing back in. “If I’d used a treatment, I would have thought it was a miracle drug,” she said.

It's no myth that excess stress can literally make your hair fall out. How does this happen? Well, it can raise androgen (male hormone) levels, which in turn can causes hair loss. "Stress may also trigger scalp problems, such as dandruff, disrupt eating habits and mess with the digestive system – all of which can have a negative impact on hair" says Anabel.
Laser light therapy is not a baldness solution, and the HairMax takes a time commitment: You have to use the product for 15 minutes a day, three days a week and you have to keep using it indefinitely to get results. Still, laser light therapy has no major side effects, and may be best for men who have noticed some increased shedding and want to maintain more of the hair they have on their head.
Finasteride (Propecia) is used in male-pattern hair loss in a pill form, taken 1 milligram per day. It is not indicated for women and is not recommended in pregnant women. Treatment is effective starting within 6 weeks of treatment. Finasteride causes an increase in hair retention, the weight of hair, and some increase in regrowth. Side effects in about 2% of males, include decreased sex drive, erectile dysfunction, and ejaculatory dysfunction. Treatment should be continued as long as positive results occur. Once treatment is stopped, hair loss resumes.[30]

"The majority of men lose their hair not through stress, or bad diet, or lack of sleep, but through the genetic trait of male pattern baldness which is hard to treat through shampoos or supplements alone. Women lose their hair for very different reasons, but the argument still stands that a lot of the hair loss products on the market are just offering false hope. That said, there are a few that really work."


3. Surgical hair replacement. If you opt for hair transplantation (which runs $5,000 and up), your dermatologist or hair-replacement surgeon will remove single hair follicles from the back of the head, near the nape of the neck, where your hair is fullest. Once those follicles are harvested, they are then dissected and reimplanted into an area of the scalp where hair is thinning. The procedure takes anywhere from three to six hours, and newly implanted hair will usually begin to grow on its own 3 to 12 months after the treatment session. Traditionally, hair transplantation required removal of an entire strip of scalp, Sadick says, but this new follicle-by-follicle technique looks more natural when it heals and allows patients to get heads of hair as dense-looking as before they started losing it.
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